Blar i Bergen Open Research Archive på forfatter "Strell, Carina"
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An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver
Fernández Moro, Carlos; Geyer, Natalie; Harrizi, Sara; Hamidi, Yousra; Söderqvist, Sara; Kuznyecov, Danyil; Tidholm Qvist, Evelina; Salmonson Schaad, Media; Hermann, Laura; Lindberg, Amanda; Heuchel, Rainer L.; Martín-Bernabé, Alfonso; Dhanjal, Soniya; Navis, Anna C.; Villard, Christina; del Valle, Andrea C.; Bozóky, Lorand; Sparrelid, Ernesto; Dirix, Luc; Strell, Carina; Östman, Arne; Schmierer, Bernhard; Vermeulen, Peter B.; Engstrand, Jennie; Bozóky, Béla; Gerling, Marco (Journal article; Peer reviewed, 2023)A perimetastatic capsule is a strong positive prognostic factor in liver metastases, but its origin remains unclear. Here, we systematically quantify the capsule’s extent and cellular composition in 263 patients with ... -
Prognostic and predictive impact of stroma cells defned by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial
Strell, Carina; Stenmark Tullberg, Axel; Edelmann, Reidunn Jetne; Akslen, Lars Andreas; Malmström, Per-Uno; Fernö, Mårten; Holmberg, Erik; Östman, Arne; Karlsson, Per (Journal article; Peer reviewed, 2021)Purpose Predictive biomarkers are needed to aid the individualization of radiotherapy (RT) in breast cancer. Cancer-associated fibroblasts have been implicated in tumor radioresistance and can be identified by platelet-derived ... -
Spatial immunophenotyping of the tumour microenvironment in non–small cell lung cancer
Backman, Max; Strell, Carina; Lindberg, Amanda; Mattsson, Johanna S.M.; Elfving, Hedvig; Brunnström, Hans; O'Reilly, Aine; Bosic, Martina; Gulyas, Miklos; Isaksson, Johan; Botling, Johan; Kärre, Klas; Jirström, Karin; Lamberg, Kristina; Pontén, Fredrik; Leandersson, Karin; Mezheyeuski, Artur; Micke, Patrick (Journal article; Peer reviewed, 2023)Introduction: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological ... -
Vessel size as a marker of survival in estrogen receptor positive breast cancer
Milosevic, Vladan; Edelmann, Reidunn Jetne; Winge, Ingeborg; Strell, Carina; Mezheyeuski, Artur; Knutsvik, Gøril; Askeland, Cecilie; Wik, Elisabeth; Akslen, Lars Andreas; Östman, Arne (Journal article; Peer reviewed, 2023)Purpose: Angiogenesis is crucial for tumor growth and is one of the hallmarks of cancer. In this study, we analyzed microvessel density, vessel median size, and perivascular a-SMA expression as prognostic biomarkers in ...